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CosaminŽDS

CosaminDS Data Sheet

CosaminDS contains the active ingredients glucosamine hydrochloride (500mg), chondroitin sulphate (400mg) and manganese gluconate (45.5mg).

Description

CosaminDS are purple and white gelatine capsules, each containing;

  • GLUCOSAMINE HYDROCHLORIDE (99+% Purity) 500mg
  • CHONDROITIN SULPHATE BOVINE (100% Purity) 400mg
  • MANGANESE GLUCOCONATE 45.5mg (EQUIVALENT MANGANESE 5mg)
  • CALCIUM ASCORBATE 80mg (EQUIVALENT ASCORBIC ACID 66mg)

Contains no added colorants, preservatives or other additives. Packaged in plastic, sealed, airtight bottles of 60 or 180 capsules containing a desiccant.

Pharmacology Actions

Glucosamine hydrochloride is a readily absorbed amino sugar found in the joints of mammals. When taken as a dietary supplement, glucosamine provides supplemental glucosamine to assist the metabolic function of cartilage and promote production of cartilage building proteins.

Chondroitin sulphate is a glycosaminoglycan (GAG) produced by cartilage and certain other body tissues. The chain length and molecular size of chondroitin sulphate in CosaminDS ensures it is over 70% absorbed. CosaminDS contains Low Molecular Weight (LMW) chondroitin sulfate.

This is important as described in the US Physicians Desk Reference as many chondroitin sulfate products are not readily absorbed in the body. Taken as a supplement, chondroitin sulphate helps maintain the structural integrity of cartilage and inhibits the metalloproteases that promote joint degeneration.

Glucosamine and chondroitin act synergistically to assist cartilage production and protect existing cartilaginous tissue.

Manganese is an essential trace element and a co-factor in the synthesis of GAGs.  Supplemental manganese ensures an adequacy of this mineral to ensure efficient synthesis of GAGs.

Indications

CosaminDS is indicated as a dietary supplement where joint dysfunction is associated with the degenerative changes of osteoarthritis, or when supplemental glucosamine and chondroitin may be considered beneficial for maintaining joint structure and function.

Contraindications and Precautions

There are no known contraindications for CosaminDS. However, persons taking anticoagulant therapy are advised to have clotting times regularly checked when taking CosaminDS. Diabetics are advised to monitor blood glucose levels regularly when taking CosaminDS. No studies have evaluated the use of CosaminDS during pregnancy or lactation. It should be taken with caution and medical advice during pregnancy and lactation.

Adverse Reactions

Safety studies with CosaminDS show no demonstrable toxicity. Some individuals may experience mild, reversible, intestinal flatulence, especially at initial dose rates. This can usually be alleviated by taking CosaminDS with meals followed by a glass of water. At maintenance rates, no disadvantages have been reported.

Please note that the glucosamine HCL used in CosaminDS is derived from crustacean shells however proteins associated with causing seafood allergy are removed during the manufacturing process. No incidents of seafood allergic reactions have been reported with the use of CosaminDS however we recommend people with such allergies seek medical advice before commencing use of CosaminDS.

Dosage and Administration

During the initial 60 day period:
Adults weighing under 90kg should take three (3) capsules daily (2 in the morning and 1 in the evening). Individuals weighing over 90kg should take two (2) capsules twice a day.
For children, consult your physician or pharmacist.

After 60 days:
The number of capsules can be gradually decreased to a level that maintains the individual. If at any time pain or discomfort reoccur the number of capsules may be increased back to your previous level.

Storage

Store in a cool, dry place.

Presentations

CosaminDS is available in two pack sizes

  • CosaminDS Monthly pack (60 Capsules)
  • CosaminDS 3-Monthly pack (180 Capsules)

CosaminDS is available through health professionals such as selected pharmacies, doctors, Health Food outlets, physiotherapists or purchase direct from Direct Order Centre.

CosaminDS is manufactured and distributed in Australia by Biocel Australia.

Biocel Australia
ABN 92 081 302 546
PO Box 89
GLENORIE NSW 2157